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Liquid Biopsy Tracker / Nanobomb Plus

Our mission is to offer sustainable, non-toxic medical engineering treatment combined with long term immunotherapy with reduced side effects, compared to systemic chemotherapy drugs and radiation therapy.

Go-AI believes early detection of cancer to deliver transformative progress in cancer survival and wider skill sets beyond cancer biology are essential, including engineers, chemists, physicists, technology developers, and behavioural and computer scientists. Integrated, interdisciplinary collaboration is key to bringing new ideas to address the challenges of early cancer detection. We believe that early detection of cancer is approaching a tipping point, as biological insight and technological capacity are increasing at an unprecedented rate and as public and private funders of research are increasingly willing to invest. (Source: Early detection of cancer | Science)

Together with Dr Balaji (Baloo) Panchapakesan, Go-AI has established an equal 50/50 partnership Nanotherapy Plus Pty Ltd.

We will implement a Test to Treat Strategy “Nanobomb Plus” to provide a comprehensive solution of early detection via a new patent pending Liquid Biopsy Tracker diagnostic tool + nanotechnology “Nanobomb” therapy + immunotherapy Checkpoint Inhibitors.

The objective of ‘Nanobomb Plus’ is to improve treatment efficacy/ survival outcome through early detection, followed by primary non-toxic therapy Nanobomb, and secondary immunotherapy to eliminate cancel cells by activating the T-cells to prevent tumour regrowth and to provide ongoing prophylaxis supported by T-cell memory.


Liquid Biopsy Tracker

A simple blood test for cancer diagnostic

Liquid Biopsy Tracker is a novel chip system designed to efficiently capture circulating tumor cells (CTCs) from blood samples. The chip combines nanoparticles able to capture CTCs, endothelial cell coatings, and micro well isolation to create a multi-modal CTC capture system. This integrated approach leverages the unique physical, chemical, and biological interactions to significantly improve capture efficiency, selectivity, and CTC viability, allowing for subsequent downstream analysis such as genomic and proteomic studies. 

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Nanobomb Plus Immunotherapy

The Nanobomb Plus Immunotherapy approach represents a groundbreaking cancer treatment that merges nanotechnology, viral oncolysis, and checkpoint blockade immunotherapy. This innovative platform uses dual-function nanoparticles, engineered as Nanobombs, to physically disrupt tumour cells, deliver viral agents, and release tumour-specific antigens. It promotes cancer cell death through oxidative stress, further boosting the immunogenicity of tumours. The immune system, activated by the release of antigens and enhanced with checkpoint inhibitors, sustains an aggressive and long-lasting response against cancer cells. This multi-modal approach exploits multiple vulnerabilities within tumours, providing an advanced solution for patients who are unresponsive to conventional treatments. 

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Strategic Partnership

Go-AI has entered into an equal strategic partnership Agreement with Dr Balaji (Baloo) Panchapakesan to jointly commercialize Nanobomb Plus: a comprehensive Test to Treat solution of Cancer Diagnostic + Nanobomb + Immunotherapy. The Parties will collaborate to expedite the introduction of advanced novel and inventive medical engineering tools for the reliable detection of cancer diseases so as to permit the timely treatment of cancers with effective targeted nanotechnology therapy at economic cost and complemented with immunotherapy checkpoint inhibitors to prevent tumour regrowth and for prophylactic application.

Dr Panchapakesan was the inventor of the Liquid Biopsy Chip and Nanobomb technologies.  

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Address

Level 1, 237 East Boundary Road 
Bentleigh East, Victoria, 3165 
Australia

Contacts

Email: contact@go-ai.com.au

Kevin Wong